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The document lists key regulatory identifiers including CTG number NCT02125786, IND #104987, and an IRB approval framework with St. Jude IRB number Pro00004349. It records protocol version history (Rev 0.1 through Rev 3.2) with activation and approval dates, and specifies the protocol document date for the latest revision. Principal investigator and study co-investigators with institutional affiliations and contact details are provided.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/a-phase-ii-trial-of-surgery-and-fractionated-re-irradiation-for-recurrent-ependymoma/272432/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/a-phase-ii-trial-of-surgery-and-fractionated-re-irradiation-for-recurrent-ependymoma/272432.png","ImageObject",300,407,{"name":92,"@type":93},"Margaret","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-07","2026-09-15",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",12,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What condition and treatment approach does the Phase II trial focus on?","Question",{"text":113,"@type":114},"The trial targets recurrent ependymoma and studies surgery together with fractionated re-irradiation.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"Which regulatory identifiers are referenced in the document?",{"text":118,"@type":114},"The document includes CTG number NCT02125786 and IND #104987, along with St. Jude IRB number Pro00004349 and IRB approval dates.",{"name":120,"@type":111,"acceptedAnswer":121},"Who are the key investigators listed in the protocol?",{"text":122,"@type":114},"Thomas E. Merchant, DO, PhD is the principal investigator, and multiple St. Jude co-investigators are listed with their departments and contact information.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},272432,1789465105,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":140,"language":141,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":142,"faqs":143,"seo_title":144,"seo_description":67,"update_tm":130,"read_time":145,"preview_page_count":4},137451207643,"https://ap-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","Official Study Title: A Phase II Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma  \nCTG Number: NCT02125786  \nDocument Date: 2/ 1/2023  \nSt. Jude  \nRERTEP  \nInitial version, dated: 12/10/2013 Resubmitted to IRB: 3/17/2014 (IRB Approved: 3/18/2014)  \nActivated: 04/21/2014  \nRev 0.1, dated: September 3, 2015 (IRB Approved: 10/22/2015) Activated: November 2, 2015 Amend 1.0, dated: September 1, 2016 (IRB Approved: 12/06/2016) Activated: December 14, 2016 Rev. 1.1 dated: July 28, 2017 (IRB Approved: 8/30/2017) Activated: September 7, 2017 Amend 2.0, dated: January 11, 2019 (IRB Approved 08-09-2019 Activated: August 19, 2019 Amend 3.0 dated: June 30, 2020 (IRB Approved: 08-11-2020) Activated: September 20, 2020 Rev. 3.1, dated: September 14, 2020 (IRB Approved: 10-27-2020) Activated:November 11, 2020 Rev. 3.2, dated January 19, 2023 (IRB Approved 02-01-2023)Activated: February 28, 2023  \nA PHASE II TRIAL OF SURGERY AND FRACTIONATED RE-IRRADIATION FOR  \nRECURRENT EPENDYMOMA  \nIND \\#104987  \nPrincipal Investigator  \nThomas E. Merchant, DO, PhD  \nDepartment of Radiation Oncology  \nSt. Jude Children’s Research Hospital  \n262 Danny Thomas Place, MS 210  \nMemphis, TN 38105  \nPhone: (901) 595-3604  \nFax: (901) 595-3113  \nEmail: [thomas.merchant@stjude.org](thomas.merchant@stjude.org)  \nRev. 3.2 dated: 1/19/2023 IRB Approval date:  \nProtocol document date: 1/19/2023  \nSt. Jude Children's Research Hospital IRB NUMBER: Pro00004349  \nIRB APPROVAL DATE: 02/01/2023  \nSt. Jude Co-Investigators  \nDavid Ellison, MD, PhD Department of Pathology  \nSt. Jude Children’s Research Hospital 262 Danny Thomas Place, MS 250 Memphis, TN 38105  \nPhone: (901) 595-3538  \nFax: (901) 595-3100  \nEmail: [david.ellison@stjude.org](david.ellison@stjude.org)  \n[Chia-ho Hua](Chia-ho Hua), PhD  \nDepartment of Radiation Oncology St. Jude Children’s Research Hospital 262 Danny Thomas Place, MS 210 Memphis, TN 38105  \nPhone: (901) 595-3610  \nFax: (901) 595-3981  \nEmail: [chia-ho.hua@stjude.org](chia-ho.hua@stjude.org)  \nBelinda Mandrell, PhD Nursing Research  \nSt. Jude Children’s Research Hospital 262 Danny Thomas Place, MS 738 Memphis, TN 38105  \nPhone: (901) 595-4209  \nFax: (901) 595-2866  \n[Email:](Email: belinda.mandrell@stjude.org)[ ](Email: belinda.mandrell@stjude.org)[belinda.mandrell@stjude.org](Email: belinda.mandrell@stjude.org)  \nHeather M. Conklin, PhD Department of Psychology  \nSt. Jude Children’s Research Hospital 262 Danny Thomas Place, MS 740 Memphis, TN 38105  \nPhone: (901) 595-3585  \nFax: (901) 595-4701  \n[Email:](Email: heather.conklin@stjude.org)[ ](Email: heather.conklin@stjude.org)[heather.conklin@stjude.org](Email: heather.conklin@stjude.org)  \nAmar Gajjar, MD Division of Neuro-Oncology Department of Oncology  \nSt. Jude Children’s Research Hospital 262 Danny Thomas Place, MS 260 Memphis, TN 38105  \nPhone: (901) 595-2615  \nFax: (901) 521-9005  \nEmail: [amar.gajjar@stjude.org](amar.gajjar@stjude.org)  \nNoah Sabin, MD Diagnostic Imaging  \nSt. Jude Children’s Research Hospital  \n262 Danny Thomas Place, MS 220  \nMemphis, TN 38105 Phone: (901) 595-6526  \nFax: (901) 595-3981  \n[Email:](Email: noah.sabin@stjude.org)[ ](Email: noah.sabin@stjude.org)[noah.sabin@stjude.org](Email: noah.sabin@stjude.org)  \nKirsten Ness, PhD  \nDivision of Epidemiology  \nDepartment of Cancer Prevention and Control St. Jude Children’s Research Hospital  \n262 Danny Thomas Place, MS 735  \nMemphis, TN 38105 Phone: (901) 595-5157  \nFax: (901) 595-5845  \n[Email:](Email: kiri.ness@stjude.org)[ ](Email: kiri.ness@stjude.org)[kiri.ness@stjude.org](Email: kiri.ness@stjude.org)  \nJohnnie Bass, AuD Rehabilitation Services  \nSt. Jude Children’s Research Hospital  \n262 Danny Thomas Place, MS 113  \nMemphis, TN 38105 Phone: (901) 595-6696  \nFax: ( 901) 595-2961  \nEmail: [johnnie.bass@stjude.org](johnnie.bass@stjude.org)  \nAustin Faught, PhD Radiation Oncology  \nSt. Jude Children’s Research Hospital  \n262 Danny Thomas Place, MS 210  \nMemphis, TN 38105 Phone: (901) 595-1121  ","cbCaipwoVc0WqCAN","https://ap.wps.com/l/cbCaipwoVc0WqCAN","pdf",1140949,166,"English","# Protocol overview\n## Study identifiers and regulatory approvals\n## Principal investigator and co-investigators","[{\"question\":\"What condition and treatment approach does the Phase II trial focus on?\",\"answer\":\"The trial targets recurrent ependymoma and studies surgery together with fractionated re-irradiation.\"},{\"question\":\"Which regulatory identifiers are referenced in the document?\",\"answer\":\"The document includes CTG number NCT02125786 and IND #104987, along with St. Jude IRB number Pro00004349 and IRB approval dates.\"},{\"question\":\"Who are the key investigators listed in the protocol?\",\"answer\":\"Thomas E. Merchant, DO, PhD is the principal investigator, and multiple St. Jude co-investigators are listed with their departments and contact information.\"}]","A Phase II Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma | PDF",418]