[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-458298-105":59,"doc-detail-458298-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","a-case-of-post-transplantation-lymphoproliferative-disorder-following-kidney-transplantation","A Case of Post-Transplantation Lymphoproliferative Disorder Following Kidney Transplantation","","Case report describing a 65-year-old man with long-standing diabetes and hypertension, previously treated hepatitis C, and a kidney transplant in 2016. He presented to a tertiary center in October 2023 with 6 months of abdominal pain, vomiting, and constipation, progressing to dehydration and abdominal distension. CT demonstrated small-bowel obstruction with a midjejunal mass, leading to exploratory laparotomy and excision. Histology confirmed diffuse large B-cell lymphoma as post-transplant lymphoproliferative disorder, with contextual discussion of PTLD presentation and diagnosis after solid organ transplantation.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/a-case-of-post-transplantation-lymphoproliferative-disorder-following-kidney-transplantation/458298/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/a-case-of-post-transplantation-lymphoproliferative-disorder-following-kidney-transplantation/458298.png","ImageObject",300,407,{"name":92,"@type":93},"Damian","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-08","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":19},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is post-transplant lymphoproliferative disorder (PTLD) in this case context?","Question",{"text":112,"@type":113},"PTLD is described as a malignancy after solid organ transplantation driven by excessive B-cell proliferation due to weakened immune surveillance.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What symptoms and initial findings led to imaging in the patient?",{"text":117,"@type":113},"He presented with 6 months of insidious abdominal pain, vomiting, constipation, dehydration, and abdominal distension, prompting further evaluation.",{"name":119,"@type":110,"acceptedAnswer":120},"How was the final diagnosis confirmed?",{"text":121,"@type":113},"Exploratory laparotomy identified a midjejunal tumor and histological examination of the excised specimen confirmed diffuse large B-cell lymphoma (DLBCL).","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},458298,1790752509,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":19,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":19,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":129,"read_time":52,"preview_page_count":4},137451208677,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","Wiley  \nCase Reports in Nephrology  \nVolume 2026, Article ID 5917161, 4 pages [https://doi.org/10.1155/crin/5917161](https://doi.org/10.1155/crin/5917161)  \nCase Report  \nA Case of Post-Transplantation Lymphoproliferative Disorder Following Kidney Transplantation  \nPunamAjay Raval , 1 John Otieno Odhiambo , 1 Hanika Patel,2 and Ahmed Sokwala 3  \n1 Department of Internal Medicine, Te Aga Khan University Hospital, Nairobi, Kenya  \n2 Department of Radiology, Te Aga Khan University Hospital, Nairobi, Kenya  \n3 Department of Nephrology, Te Aga Khan University Hospital, Nairobi, Kenya  \nCorrespondence should be addressed to Punam Ajay Raval; [punam.raval2@scholar.aku.edu](punam.raval2@scholar.aku.edu)  \nReceived 19 July 2025; Revised 10 November 2025; Accepted 13 November 2025  \nAcademic Editor: Poorani Gurumallesh Prabu  \nCopyright © 2026 PunamAjay Raval et al. Case Reports inNephrology published by John Wiley & Sons Ltd. Tis is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.  \nTis was a case of a 65-year-old gentleman known to have diabetes mellitus and hypertension since 2012 and post renal transplantation in 2016 . He had also been treated for hepatitis C infection in the past. His regular medications included nebivolol  \n5 mg once a day, tacrolimus 4 mg twice a day, mycophenolate mofetil 500 mg twice a day, prednisolone 5 mg once a day, and insulin–novomix 14 units in the morning and 6 units at night. He presented to a tertiary teaching hospital in Kenya in October 2023 with abdominal pain, vomiting, and constipation on and of for 6 months, worse in the month prior to presentation. His examination was positive for dehydration, abdominal distension, and generalized abdominal tenderness. He had a normal hematological profle and renal function. A CT scan of the abdomen showed features of small bowel obstruction from the distal ileal to distal jejunal bowel loops. Te patient underwent an exploratory laparotomy with intraoperative fndings of a midjejunal tumor completely obstructing the lumen with proximal dilatation. Te tumor was subsequently excised. Histological specimen confrmed difuse large B-cell lymphoma (DLBCL) as his fnal diagnosis.  \n1. Background  \nPost-transplant lymphoproliferative disorders (PTLDs) are important malignancies after solid organ transplantation (SOT) [1] and arise from excessive B-cell proliferation caused by weakened immune surveillance. B cells can become infected with Epstein–Barr virus (EBV) either through viral reactivation after transplantation, primary EBV infection via the transplanted organ, or environmental exposure. Most PTLD cases (over 85%) typically occur within the frst year following transplantation. PTLD caused by T-cell proliferation is rarerand is usually EBV negative [2]. Lymphoma accounts for 21% of all malignancies in SOT recipients as compared to 4% and 5% in immunocompetent individuals, respectively, in men and women [3]. Clinically, PTLD may manifest either as localized lesion or as systemic disease. Tissue diagnosis (histopathology)  \nis essential for PTLD diagnosis, in addition to a clear evidence of EBV DNA, RNA, or protein material [1].  \n2. Case Presentation  \nTis was a case of a 65-year-old gentleman known to have diabetes mellitus and hypertension since 2012 and post right renal transplantation in 2016 due to hypertensive nephropathy, with prior history of treatment of hepatitis C. He presented to the hospital in October 2023 with a 6-month history of insidious abdominal pain, vomiting, progressive loss of appetite, and constipation. His past medical history was remarkable for being treated with antibiotics and symptomatic relief as an outpatient in peripheral facilities. At presentation, he was dehydrated with a pulse rate of 89 bpm and raised blood pressure of 153/86 mmHg. Systemic  \n2 Case Reports in Nephrology  \nexam was posit","cbCaig84D3sWN7Fj","https://ap.wps.com/l/cbCaig84D3sWN7Fj","pdf",2017303,"English","# Background\n# Case Presentation\n## Imaging\n## Management\n## Intraoperative Findings\n## Histopathology","[{\"question\":\"What is post-transplant lymphoproliferative disorder (PTLD) in this case context?\",\"answer\":\"PTLD is described as a malignancy after solid organ transplantation driven by excessive B-cell proliferation due to weakened immune surveillance.\"},{\"question\":\"What symptoms and initial findings led to imaging in the patient?\",\"answer\":\"He presented with 6 months of insidious abdominal pain, vomiting, constipation, dehydration, and abdominal distension, prompting further evaluation.\"},{\"question\":\"How was the final diagnosis confirmed?\",\"answer\":\"Exploratory laparotomy identified a midjejunal tumor and histological examination of the excised specimen confirmed diffuse large B-cell lymphoma (DLBCL).\"}]","A Case of Post-Transplantation Lymphoproliferative Disorder Following Kidney Transplantation | PDF"]