[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-445181-105":59,"doc-detail-445181-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","a-case-of-giant-retroperitoneal-ganglioneuroma-encasing-major-vascular-structures","A case of giant retroperitoneal ganglioneuroma encasing major vascular structures","","Ganglioneuroma (GN) is a rare benign tumor arising from sympathetic ganglion cells and often developing in the retroperitoneum. A 33-year-old woman presented with intermittent low back pain for two months. Imaging identified a large retroperitoneal mass encasing the inferior vena cava and right renal vein, with imaging suspicion for GN or lymphangioma. Laparotomy exploration enabled en bloc resection with vascular repair, and pathology confirmed mature ganglion cells (SOX10, S100). Recovery was uneventful with well-being at four-month follow-up.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/a-case-of-giant-retroperitoneal-ganglioneuroma-encasing-major-vascular-structures/445181/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/a-case-of-giant-retroperitoneal-ganglioneuroma-encasing-major-vascular-structures/445181.png","ImageObject",300,407,{"name":92,"@type":93},"CatatanPagi","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-03","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":81},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What symptoms and imaging findings characterized the patient’s retroperitoneal mass?","Question",{"text":112,"@type":113},"The patient reported intermittent low back pain for two months. CT and MRI showed a large retroperitoneal mass with encasing growth along the inferior vena cava and right renal vein, raising suspicion for GN or lymphangioma.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the diagnosis confirmed after surgery?",{"text":117,"@type":113},"After open exploration, complete resection and vascular repair were performed. Pathology confirmed mature ganglion cells with SOX10 and S100 positivity, consistent with ganglioneuroma.",{"name":119,"@type":110,"acceptedAnswer":120},"Why is multidisciplinary planning important for retroperitoneal tumors encasing major vessels?",{"text":121,"@type":113},"Retroperitoneal GN can mimic other entities on imaging and may involve major vascular structures. The case highlights the need for imaging assessment and multidisciplinary collaboration to enable safe resection and vascular management.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},445181,1790993906,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":81,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":81,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":39},962090894170,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","Journal of Surgical Case Reports, 2026, 1, rjaf1034  \n[https://doi.org/10.1093/jscr/rjaf1034](https://doi.org/10.1093/jscr/rjaf1034)  \nCase Report  \nCase Report  \nA case of giant retroperitoneal ganglioneuroma encasing major vascular structures  \nLei Xiao1 , 2 , Guanqiang Li1 , Bo Hu1 , Yuan Sun1 , Xicheng Zhang1 , Xianchen Huang1 , *  \n1 Department of Vascular Surgery and Intervention, The Fourth Affiliated Hospital of Soochow University, Suzhou 215123, China  \n2 Medical College of Soochow University, Suzhou 215123, China  \n*Corresponding author. The Fourth Affiliated Hospital of Soochow University, 9 ChongWen Road, Suzhou Industrial Park, Suzhou City, Jiangsu Province, China.  \nE-mail: [dushuhu777@foxmail.com](dushuhu777@foxmail.com)  \nAbstract  \nGanglioneuroma (GN) is a rare benign tumor arising from sympathetic ganglion cells, often located in the retroperitoneum. We report a case of a 33-year-old woman presenting with intermittent low back pain for 2 months. Imaging revealed a large retroperitoneal mass (24 × 36 × 68 mm) encasing the inferior vena cava (IVC) and right renal vein, with a high suspicion for GN or lymphangioma. Surgical exploration via laparotomy confirmed a tough, adherent mass (5 × 8 × 10 cm) intimately associated with the IVC and renal vessels. Complete resection with vascular repair was performed. Pathology confirmed mature ganglion cells positive for SOX10 and S100, consistent with GN. The patient recovered uneventfully and remained well at 4-month follow-up.  \nKeywords: ganglioneuroma; retroperitoneal mass; vascular encasement; surgical resection  \nIntroduction  \nGanglioneuroma (GN) is a rare benign tumor derived from neural crest cells of the sympathetic ganglia, with an estimated incidence of 0 . 1%–0 . 2% among all retroperitoneal neoplasms [1] . Predominantly affecting young adults, GN often presents asymptomatically until achieving significant size, leading to delayed diagnosis and potential complications from mass effect or vascular encasement [2] . Retroperitoneal GN frequently mimics more common entities like lymphangioma or sarcoma on imaging, complicating preoperative planning, particularly when encasing major vessels such as the inferior vena cava (IVC) or renal veins—necessitating multidisciplinary approaches for safe resection [3] .  \nHere, we report a case of a 33-year-old woman with a giant retroperitoneal GN intimately encasing the IVC and right renal vessels, managed via open en bloc resection with vascular reconstruction. This case emphasizes that even emerging hospitals must prioritize imaging reporting and multidisciplinary collaboration to actively manage patients with retroperitoneal masses encasing major blood vessels.  \nCase report  \nA 33-year-old woman was admitted due to ‘intermittent low back pain for 2 months.’ She denied a history of hypertension, diabetes, or familial hereditary tumors. Physical examination revealed: alert and oriented, with stable vital signs. The abdomen was soft and flat, without superficial lymphadenopathy or superficial  \nvaricosities; no tenderness, rebound tenderness, or peritoneal irritation signs; no palpable abdominal mass; liver and spleen not palpable below the costal margin; negative renal angle percussion pain bilaterally; negative shifting dullness; and normal bowel sounds.  \nContrast-enhanced computed tomography (CT) on admission showed an occupying lesion at the right renal hilum and adjacent to the IVC, with clear borders, uniformly low density, and heterogeneous progressive enhancement post-contrast, suggestive of a possible lymphangioma (Fig. 1a) . Subsequent magnetic resonance imaging (MRI) with plain and contrastenhanced sequences revealed a right retroperitoneal mass measuring ∼24 × 36 × 68 mm . OnT1WI,it appeared as a uniformly low signal; on T2WI, as heterogeneous high signal. Post-contrast, it showed clear borders with heterogeneous enhancement. The lesion encased the IVC and right renal vein in an \"encasing\"growth pattern, withou","cbCaiqsNkXJkQOfr","https://ap.wps.com/l/cbCaiqsNkXJkQOfr","pdf",290176,"English","# Abstract\n# Introduction\n# Case report","[{\"question\":\"What symptoms and imaging findings characterized the patient’s retroperitoneal mass?\",\"answer\":\"The patient reported intermittent low back pain for two months. CT and MRI showed a large retroperitoneal mass with encasing growth along the inferior vena cava and right renal vein, raising suspicion for GN or lymphangioma.\"},{\"question\":\"How was the diagnosis confirmed after surgery?\",\"answer\":\"After open exploration, complete resection and vascular repair were performed. Pathology confirmed mature ganglion cells with SOX10 and S100 positivity, consistent with ganglioneuroma.\"},{\"question\":\"Why is multidisciplinary planning important for retroperitoneal tumors encasing major vessels?\",\"answer\":\"Retroperitoneal GN can mimic other entities on imaging and may involve major vascular structures. The case highlights the need for imaging assessment and multidisciplinary collaboration to enable safe resection and vascular management.\"}]","A case of giant retroperitoneal ganglioneuroma encasing major vascular structures | PDF",1790710542]