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A two-center prospective design enrolled 72 patients with obstructive jaundice, assigning 36 to a 3D reconstruction intervention group and 36 to conventional ERCP controls. The primary outcomes included technical success, procedure duration, X-ray exposure time, clinical success defined as a ≥50% bilirubin reduction within 5 days, and adverse events. Compared with conventional ERCP, 3D-assisted ERCP significantly reduced cannulation time and X-ray exposure time while maintaining comparable technical and clinical success rates, with no procedure-related mortality reported.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/3d-assisted-ercp-prospective-two-center-study-enhances-cannulation-efficiency-in-malignant-biliary-obstruction/370072/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/3d-assisted-ercp-prospective-two-center-study-enhances-cannulation-efficiency-in-malignant-biliary-obstruction/370072.png","ImageObject",300,407,{"name":92,"@type":93},"hdkawk","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-03","2026-09-23",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",14,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What problem does the study address in ERCP for malignant biliary obstruction?","Question",{"text":113,"@type":114},"ERCP can be more challenging when pancreatic cancer is complicated by obstructive jaundice, often prolonging cannulation time. The study targets whether 3D reconstruction assistance can improve efficiency.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How was the 3D-assisted ERCP intervention implemented and compared?",{"text":118,"@type":114},"A two-center prospective study enrolled 72 patients. The intervention group received 3D reconstruction before ERCP for planning and intraoperative guidance, while the control group underwent conventional ERCP.",{"name":120,"@type":111,"acceptedAnswer":121},"What outcomes showed significant improvement with 3D-assisted ERCP?",{"text":122,"@type":114},"3D-assisted ERCP significantly reduced cannulation time and X-ray exposure time for both patients and physicians. Technical success, clinical success, and adverse event rates were not significantly different between groups.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},370072,1790270568,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":34,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145},3985747859855,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","3D-assisted ERCP enhancescannulation efficiency in malignant biliary obstruction: a prospective two-center study  \nMengke Fan, MDa , Guochen Shang, MDa,b , Songxiang Liu, MDc,d,e , Tianhang Li, MDa , Dongliang Li, MDf, Zhen Ding, MDg ,*, Zhewei Ye, MDc,d ,*, Rong Lin, MDa ,*  \nBackground and Aims: Endoscopic retrograde cholangiopancreatography (ERCP)-guided biliary drainage is the standard treatment for malignant biliary obstruction in patients who are not candidates for curative surgery. However, ERCP can be more challenging in patients with pancreatic cancer complicated by obstructive jaundice, often leading to prolonged cannulation times. This study aimed to evaluate the efficacy of three-dimensional (3D) reconstruction-assisted ERCP in treating patients with pancreatic cancer complicated by malignant biliary obstruction.  \nMethods: We performed a two-center prospective study including 72 patients diagnosed with pancreatic cancer complicated by obstructive jaundice. The 36 patients who underwent 3D reconstruction before ERCP constituted the intervention group, while the remaining patients, who received conventional ERCP without 3D assistance, served as the control group. Outcomes evaluated included technical success, procedure duration, X-ray exposure time, clinical success (defined as a ≥50% reduction in serum bilirubin within 5 days), and adverse events.  \nResults: 3D models were successfully constructed for patients in the intervention group and were used for both preoperative planning and intraoperative guidance during ERCP. Compared to conventional ERCP, 3D-assisted ERCP significantly reduced cannulation time (16 min [IQR: 13–30] vs. 13.5 min [IQR: 9–21], P = 0.036) and X-ray exposure time (40 .5 s [IQR: 28–69] vs. 34.5 s [IQR: 24–45.5], P = 0.034) for both patients and physicians. No significant differences were observed between the two groups in terms of technical success rates (97 .2% vs. 100%, P = 1), clinical success rates (77 .8% vs. 83.3%, P = 0.77) or adverse event rates (19 .44% vs. 13.89%, P = 0.75) . Additionally, no procedure-related mortality occurred.  \nConclusions: 3D-assisted ERCP significantly reduces the X-ray exposure time and shortens cannulation time for both patients and physicians, making it a valuable tool for treating malignant biliary obstruction.  \nHighlights: This prospective two-center study demonstrates that 3D reconstruction-assisted ERCP can significantly reduce X-ray exposure time and overall procedure duration, thereby enhancing safety and efficiency in the management of malignant biliary obstruction.  \nKeywords: biliary drainage, endoscopic retrograde cholangiopancreatography, malignant biliary obstruction, pancreatic cancer, three-dimensional reconstruction  \nIntroduction  \nPancreatic cancer is one of the most common malignant tumor of the digestive system. The data showed that the overall 5-year  \nsurvival rate for all stages of pancreatic cancer is only 5%[1,2] . Approximately 70% of patients with pancreatic cancer are diagnosed with malignant biliary obstruction[3,4], which may lead to  \naDepartment of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, bDepartment of Gastroenterology, The First Affiliated Hospital of Shihezi University, Shihezi, China, cDepartment of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, dIntelligent Medical Laboratory, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, eNanyang Technological University, Singapore, fDepartment of General Surgery, Lu’An Affiliated Hospital of Anhui Medical University, Lu’An, Anhui, China and gEndoscopy Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China  \nMengke Fan, Guochen Shang, Songxiang Liu, and Tianhang Li contributed equally to this work and share first authorship.  \nSponsorships or co","cbCaikc8zORnLQ6j","https://ap.wps.com/l/cbCaikc8zORnLQ6j","pdf",474054,"English","# Background and Aims\n# Methods\n# Results\n# Conclusions\n# Highlights\n# Keywords","[{\"question\":\"What problem does the study address in ERCP for malignant biliary obstruction?\",\"answer\":\"ERCP can be more challenging when pancreatic cancer is complicated by obstructive jaundice, often prolonging cannulation time. The study targets whether 3D reconstruction assistance can improve efficiency.\"},{\"question\":\"How was the 3D-assisted ERCP intervention implemented and compared?\",\"answer\":\"A two-center prospective study enrolled 72 patients. The intervention group received 3D reconstruction before ERCP for planning and intraoperative guidance, while the control group underwent conventional ERCP.\"},{\"question\":\"What outcomes showed significant improvement with 3D-assisted ERCP?\",\"answer\":\"3D-assisted ERCP significantly reduced cannulation time and X-ray exposure time for both patients and physicians. Technical success, clinical success, and adverse event rates were not significantly different between groups.\"}]","3D-assisted ERCP - Prospective two-center study - enhances cannulation efficiency in malignant biliary obstruction | PDF",1790186582,18]