[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-27554-en":3,"doc-seo-27554-105":27,"detail-sidebar-cat-0-en-105":69},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":4,"is_deleted":4,"is_public":20,"is_downloadable":20,"audit_status":20,"page_count":20,"language":21,"language_code":22,"site_id":23,"html_lang":22,"table_of_contents":15,"faqs":15,"seo_title":24,"seo_description":14,"update_tm":25,"read_time":26},27554,549758146520,"Patrick","https://ap-avatar.wpscdn.com/avatar/80002397d8c0411e94?_k=1775819394049821470",7,"Healthcare","3 Diuretics - Osmotic","This document offers a concise overview of osmotic diuretics, detailing their mechanism of action, therapeutic indications, and potential adverse effects. Osmotic diuretics function by increasing the density of the glomerular filtrate, thereby inhibiting water reabsorption and promoting its excretion as urine. They are utilized as adjuncts in treating acute oliguric renal failure, edema, increased intracranial or intraocular pressure, and toxic overdoses. Additionally, they serve as GU irrigants during transurethral procedures with a 2.5–5% solution. Adverse effects span across central nervous system (CNS), with symptoms like confusion and headache; otolaryngologic (EENT), including blurred vision and rhinitis; cardiovascular (CV), manifesting as transient volume expansion, chest pain, heart failure, pulmonary edema, and tachycardia; gastrointestinal (GI), with nausea, thirst, and vomiting; genitourinary (GU), potentially leading to renal failure and urinary retention; and fluid and electrolyte (F and E) imbalances such as dehydration, hyperkalemia, hypernatremia, hypokalemia, and hyponatremia. Local effects include phlebitis at the IV site. Nursing interventions emphasize frequent monitoring of blood pressure, pulse, intake and output ratios, daily weight, and assessment for signs of electrolyte imbalance. Patients should be advised to avoid alcohol and monitor serum potassium levels. Interactions with Digoxin are noted, increasing the risk of toxicity due to hypokalemia. Symptoms of fluid and electrolyte imbalance are detailed, including dry mouth, thirst, weakness, lethargy, drowsiness, restlessness, confusion, muscle pain or cramps, gastrointestinal disturbances, hypotension, oliguria, tachycardia, and seizures. Contraindications include active intracranial bleeding (except during craniotomy), hypersensitivity, anuria, dehydration, and severe pulmonary edema or congestion. The generic name for this class of diuretic is Mannitol.","","cbCaip3B5SpDOOIb","https://ap.wps.com/l/cbCaip3B5SpDOOIb","pdf",600192,1,"English","en",105,"3 Diuretics - Osmotic | PDF",1778275557,3,{"code":4,"msg":28,"data":29},"ok",{"site_id":23,"language":22,"slug":30,"title":13,"keywords":15,"description":14,"schema_data":31,"social_meta":64,"head_meta":66,"extra_data":68,"updated_unix":25},"3-diuretics-osmotic",{"@graph":32,"@context":63},[33,49],{"@type":34,"itemListElement":35},"BreadcrumbList",[36,40,44,46],{"item":37,"name":38,"@type":39,"position":20},"https://docshare.wps.com","Home","ListItem",{"item":41,"name":42,"@type":39,"position":43},"https://docshare.wps.com/document/","Document",2,{"item":45,"name":12,"@type":39,"position":26},"https://docshare.wps.com/document/healthcare/",{"item":47,"name":13,"@type":39,"position":48},"https://docshare.wps.com/document/3-diuretics-osmotic/27554",4,{"url":47,"name":13,"@type":50,"author":51,"headline":13,"publisher":53,"fileFormat":56,"description":14,"dateModified":57,"datePublished":57,"encodingFormat":56,"isAccessibleForFree":58,"interactionStatistic":59},"DigitalDocument",{"name":9,"@type":52},"Person",{"url":37,"name":54,"@type":55},"DocShare","Organization","application/pdf","2026-05-08",true,{"@type":60,"interactionType":61,"userInteractionCount":4},"InteractionCounter",{"@type":62},"ViewAction","https://schema.org",{"og:url":47,"og:type":65,"og:title":13,"og:site_name":54,"og:description":14},"article",{"robots":67,"canonical":47},"index,follow",{"doc_id":7,"site_id":23},{"code":4,"msg":5,"data":70},[71,75,79,83,88,93,96,101,106,109,113],{"id":20,"doc_module":4,"doc_module_name":42,"category_name":72,"show_sort_weight":73,"slug":74},"Story & Novel",90,"story-novel",{"id":43,"doc_module":4,"doc_module_name":42,"category_name":76,"show_sort_weight":77,"slug":78},"Literature",80,"literature",{"id":48,"doc_module":4,"doc_module_name":42,"category_name":80,"show_sort_weight":81,"slug":82},"Exam",70,"exam",{"id":84,"doc_module":4,"doc_module_name":42,"category_name":85,"show_sort_weight":86,"slug":87},5,"Comic",60,"comic",{"id":89,"doc_module":4,"doc_module_name":42,"category_name":90,"show_sort_weight":91,"slug":92},6,"Technology",50,"technology",{"id":11,"doc_module":4,"doc_module_name":42,"category_name":12,"show_sort_weight":94,"slug":95},40,"healthcare",{"id":97,"doc_module":4,"doc_module_name":42,"category_name":98,"show_sort_weight":99,"slug":100},8,"Research & Report",30,"research-report",{"id":102,"doc_module":4,"doc_module_name":42,"category_name":103,"show_sort_weight":104,"slug":105},9,"Religion & Spirituality",20,"religion-spirituality",{"id":104,"doc_module":4,"doc_module_name":42,"category_name":107,"show_sort_weight":104,"slug":108},"World Cup","world-cup",{"id":110,"doc_module":4,"doc_module_name":42,"category_name":111,"show_sort_weight":110,"slug":112},10,"Lifestyle","lifestyle",{"id":114,"doc_module":4,"doc_module_name":42,"category_name":115,"show_sort_weight":84,"slug":116},19,"General","general"]