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The multidisciplinary IE Working Group assessed the ESC recommendations and concluded that most could be endorsed, with specific modifications. It presents a refined and simplified antibiotic prophylactic regimen and an updated table to support analysis of suspected blood culture-negative IE, reaffirming the Endocarditis Team’s pivotal role and strengthening imaging recommendations.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/2023-european-society-of-cardiology-guidelines-for-the-management-of-infective-endocarditis-statement-of-endorsement/458122/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/2023-european-society-of-cardiology-guidelines-for-the-management-of-infective-endocarditis-statement-of-endorsement/458122.png","ImageObject",300,407,{"name":92,"@type":93},"Theodore","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-05","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",12,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What is the purpose of the NVVC endorsement statement?","Question",{"text":113,"@type":114},"It reviews the 2023 ESC guidelines for infective endocarditis and states which recommendations the Dutch IE Working Group endorses, including specific modifications suited to Netherlands clinical practice.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What key updates are highlighted by the IE Working Group?",{"text":118,"@type":114},"The statement emphasizes a refined and simplified antibiotic prophylactic regimen, updates to guidance for suspected blood culture-negative IE, and reinforced recommendations for the Endocarditis Team and cardiac/extracardiac imaging.",{"name":120,"@type":111,"acceptedAnswer":121},"Which additional topics are strengthened beyond general recommendation areas?",{"text":122,"@type":114},"The endorsement includes reinforced surgical evaluation criteria in the setting of neurological complications, addresses an advised disregard of a specific early-prosthetic-valve surgery recommendation, and proposes device-related guidance for reimplantation after IE.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},458122,1790816701,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":140,"language":141,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":142,"faqs":143,"seo_title":144,"seo_description":67,"update_tm":145,"read_time":146,"preview_page_count":4},7971461740886,"https://ap-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","NVVC Endorsements  \nNeth Heart J (2026) 34 (Suppl 1):S1–S13  \n[https://doi.org/10.1007/s12471-025-02010-w](https://doi.org/10.1007/s12471-025-02010-w)  \n2023 European Society of Cardiology guidelines for the management of infective endocarditis  \nStatement of endorsement by the NVVC  \nFull version  \nAnnelot J. L. Peijster  · Cees van Nieuwkoop · Ruud W. M. Keunen · Susanne Felix · Berend J. van Welzen · Ilse J. E. Kouijzer · C. H. Edwin Boel · Nelianne J. Verkaik · Ka Yan Lam · Robert J. M. Klautz ·  \nAndor W. J. M. Glaudemans · Ricardo P. J. Budde · Alexander H. Maass · Reinoud E. Knops · Otto Kamp · Wilco Tanis  \nReceived: 16 September 2025 / Accepted: 1 December 2025 / Published online: 18 December 2025 © The Author(s) 2025  \nAbstract This review evaluates the 2023 European Society of Cardiology (ESC) guidelines for the management of infective endocarditis (IE) and offers insights into topics particularly relevant to clinical practice in the Netherlands. The multidisciplinary IE Working Group assessed all ESC recommendations and concluded that the majority could be endorsed, albeit with certain modifications. The IE Working Group presents a refined (and simplified) antibiotic prophylactic regimen and an updated table to guide the anal-  \n\n| Endorsement This paper was initiated and endorsed by the Dutch Society of Cardiology (Nederlandse Vereniging voor Cardiologie, NVVC) . In addition, it underwent final-stage review and approval by the Dutch Society of Internal Medicine (Nederlandse Internisten Vereniging, NIV), the Netherlands Society for Cardiothoracic Surgery (Nederlandse Vereniging voor Thoraxchirurgie, NVT), the Dutch Society of Radiology (Nederlandse Vereniging voor Radiologie, NVvR), and the ENDOCOR Working Group. |\n| --- |\n| Supplementary Information The online version of this article ([https://doi.org/10.1007/s12471-025-02010-w](https://doi.org/10.1007/s12471-025-02010-w)) contains supplementary material, which is available to authorized users. |\n\nA. J. L. Peijster (􀀂) · R. E. Knops · O. Kamp · W. Tanis Department of Cardiology, Amsterdam University Medical Centre, Amsterdam, The Netherlands [a.j.l.peijster@amsterdamumc.nl](a.j.l.peijster@amsterdamumc.nl)  \nA. J. L. Peijster · W. Tanis  \nDepartment of Cardiology, Haga Teaching Hospital, The Hague, The Netherlands  \nC. van Nieuwkoop  \nDepartment of Internal Medicine, Haga Teaching Hospital, The Hague, The Netherlands  \nysis of suspected blood culture-negative IE. Furthermore, the pivotal role of the Endocarditis Team in the management of patients with suspected and confirmed IE was reaffirmed, along with reinforced recommendations for nearly all cardiac and extracardiac imaging in these cases. Notably, a preliminary recommendation was issued for switching to oral antibiotic therapy in patients with native valve endocarditis caused by viridans streptococci, while awaiting the revision of the Dutch Working Group on Antibiotic Pol-  \nR. W. M. Keunen  \nDepartment of Neurology, Haga Teaching Hospital, The Hague, The Netherlands  \nS. Felix  \nDepartment of Cardiology, Catharina Hospital, Eindhoven, The Netherlands  \nB. J. van Welzen  \nDepartment of Infectious Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands  \nI. J. E. Kouijzer  \nDepartment of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands  \nC. H. E. Boel  \nDepartment of Medical Microbiology, University Medical Centre Utrecht, Utrecht, The Netherlands  \nN. J. Verkaik  \nDepartment of Microbiology, Erasmus Medical Centre, Rotterdam, The Netherlands  \nK. Y. Lam  \nDepartment of Cardiothoracic Surgery, Catharina Hospital, Eindhoven, The Netherlands  \n2023 European Society of Cardiology guidelines for the management of infective endocarditis  \nS1  \nNVVC Endorsements  \nicy (SWAB) IE guideline. In addition, the surgical recommendations were evaluated and revised, including improved clinical criteria in case of cardiac surgery following neurological complications of IE and an advised ","cbCaivjybPmIrIha","https://ap.wps.com/l/cbCaivjybPmIrIha","pdf",4077092,13,"English","# Abstract\n# Endorsement\n# Supplementary Information\n# Keywords\n# Introduction","[{\"question\":\"What is the purpose of the NVVC endorsement statement?\",\"answer\":\"It reviews the 2023 ESC guidelines for infective endocarditis and states which recommendations the Dutch IE Working Group endorses, including specific modifications suited to Netherlands clinical practice.\"},{\"question\":\"What key updates are highlighted by the IE Working Group?\",\"answer\":\"The statement emphasizes a refined and simplified antibiotic prophylactic regimen, updates to guidance for suspected blood culture-negative IE, and reinforced recommendations for the Endocarditis Team and cardiac/extracardiac imaging.\"},{\"question\":\"Which additional topics are strengthened beyond general recommendation areas?\",\"answer\":\"The endorsement includes reinforced surgical evaluation criteria in the setting of neurological complications, addresses an advised disregard of a specific early-prosthetic-valve surgery recommendation, and proposes device-related guidance for reimplantation after IE.\"}]","2023 European Society of Cardiology guidelines for the management of infective endocarditis - Statement of endorsement | PDF",1790751702,33]