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The multidisciplinary IE Working Group assessed all ESC recommendations and concluded that most could be endorsed, while incorporating refinements suited to Dutch clinical care. Key endorsed updates include a refined antibiotic prophylactic regimen, guidance for suspected blood culture-negative IE, and strengthened emphasis on the Endocarditis Team’s role.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/2023-european-society-of-cardiology-guidelines-for-the-management-of-infective-endocarditis-statement-of-endorsement-by-the-nvvc/458117/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/2023-european-society-of-cardiology-guidelines-for-the-management-of-infective-endocarditis-statement-of-endorsement-by-the-nvvc/458117.png","ImageObject",300,407,{"name":92,"@type":93},"Theodore","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",14,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What is the purpose of the NVVC endorsement statement for the 2023 ESC infective endocarditis guideline?","Question",{"text":113,"@type":114},"It provides a condensed endorsement of the 2023 ESC IE guideline tailored to topics relevant to Dutch clinical practice, including selected adjustments and emphasis areas.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"Which major recommendations were assessed for endorsement by the multidisciplinary IE Working Group?",{"text":118,"@type":114},"The group reviewed ESC recommendations across prevention, diagnostic criteria, multimodality imaging, oral antibiotic therapy, surgical indications, and timing, and concluded that most could be endorsed.",{"name":120,"@type":111,"acceptedAnswer":121},"What key clinical roles and treatment-related updates are highlighted in the endorsed statement?",{"text":122,"@type":114},"The statement reinforces the pivotal role of the Endocarditis Team, presents a refined antibiotic prophylactic regimen, and updates guidance for analysis of suspected blood culture-negative IE.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},458117,1790817773,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":140,"language":141,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":142,"faqs":143,"seo_title":144,"seo_description":67,"update_tm":145,"read_time":146,"preview_page_count":4},7971461740886,"https://ap-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","NVVC Endorsements  \nNeth Heart J (2026) 34:7–17  \n[https://doi.org/10.1007/s12471-025-0201](https://doi.org/10.1007/s12471-025-0201)1-9  \n2023 European Society of Cardiology guidelines for the management of infective endocarditis  \nStatement of endorsement by the NVVC  \nShort version  \nAnnelot J. L. Peijster  · Cees van Nieuwkoop · Ruud W. M. Keunen · Susanne Felix · Berend J. van Welzen · Ilse J. E. Kouijzer · C. H. Edwin Boel · Nelianne J. Verkaik · Ka Yan Lam · Robert J. M. Klautz ·  \nAndor W. J. M. Glaudemans · Ricardo P. J. Budde · Alexander H. Maass · Reinoud E. Knops · Otto Kamp · Wilco Tanis  \nReceived: 16 September 2025 / Accepted: 2 December 2025 / Published online: 18 December 2025 © The Author(s) 2025  \nAbstract This review evaluates the 2023 European Society of Cardiology (ESC) guidelines for the management of infective endocarditis (IE) and offers insights into topics particularly relevant to clinical practice in the Netherlands. The multidisciplinary IE Working Group assessed all ESC recommendations and concluded that the majority could be endorsed,  \n\n| Endorsement The full version of this paper was initiated and endorsed by the Dutch Society of Cardiology (Nederlandse Vereniging voor Cardiologie, NVVC) . In addition, it underwent final-stage review and approval by the Dutch Society of Internal Medicine (Nederlandse Internisten Vereniging, NIV), the Netherlands Society for Cardiothoracic Surgery (Nederlandse Vereniging voor Thoraxchirurgie, NVT), the Dutch Society of Radiology (Nederlandse Vereniging voor Radiologie, NVvR), and the ENDOCOR Working Group. |\n| --- |\n| Statement This article presents a condensed version of the complete IE endorsement paper, focusing on selected aspects only. For comprehensive coverage, readers are referred to the full online version ([https://doi.org/10.1007/](https://doi.org/10.1007/)[ ](https://doi.org/10.1007/)[s12471-025-02010-w](s12471-025-02010-w)) . |\n| Supplementary Information The online version of this article ([https://doi.org/10.1007/s12471-025-02011-9](https://doi.org/10.1007/s12471-025-02011-9)) contains supplementary material, which is available to authorized users. |\n\nA. J. L. Peijster (􀀂) · R. E. Knops · O. Kamp · W. Tanis Department of Cardiology, Amsterdam University Medical Centre, Amsterdam, The Netherlands [a.j.l.peijster@amsterdamumc.nl](a.j.l.peijster@amsterdamumc.nl)  \nA. J. L. Peijster · W. Tanis  \nDepartment of Cardiology, Haga Teaching Hospital, The Hague, The Netherlands  \nalbeit with certain modifications. The IE Working Group presents a refined (and simplified) antibiotic prophylactic regimen and an updated table to guide the analysis of suspected blood culture-negative IE. Furthermore, the pivotal role of the Endocarditis Team in the management of patients with suspected and confirmed IE was reaffirmed, along with reinforced  \nC. van Nieuwkoop  \nDepartment of Internal Medicine, Haga Teaching Hospital, The Hague, The Netherlands  \nR. W. M. Keunen  \nDepartment of Neurology, Haga Teaching Hospital, The Hague, The Netherlands  \nS. Felix  \nDepartment of Cardiology, Catharina Hospital, Eindhoven, The Netherlands  \nB. J. van Welzen  \nDepartment of Infectious Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands  \nI. J. E. Kouijzer  \nDepartment of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands  \nC. H. E. Boel  \nDepartment of Medical Microbiology, University Medical Centre Utrecht, Utrecht, The Netherlands  \nN. J. Verkaik  \nDepartment of Microbiology, Erasmus Medical Centre, Rotterdam, The Netherlands  \nK. Y. Lam  \nDepartment of Cardiothoracic Surgery, Catharina Hospital, Eindhoven, The Netherlands  \n2023 European Society of Cardiology guidelines for the management of infective endocarditis  \n7  \nNVVC Endorsements  \nrecommendations for nearly all cardiac and extracardiac imaging in these cases. Most notable, a preliminary recommendation was issued for switching to oral antibiotic therapy in patients with native valv","cbCait3qsBs89HCH","https://ap.wps.com/l/cbCait3qsBs89HCH","pdf",3760081,11,"English","# Abstract\n# Endorsement\n## Statement of endorsement by the NVVC\n# Keywords\n# Introduction","[{\"question\":\"What is the purpose of the NVVC endorsement statement for the 2023 ESC infective endocarditis guideline?\",\"answer\":\"It provides a condensed endorsement of the 2023 ESC IE guideline tailored to topics relevant to Dutch clinical practice, including selected adjustments and emphasis areas.\"},{\"question\":\"Which major recommendations were assessed for endorsement by the multidisciplinary IE Working Group?\",\"answer\":\"The group reviewed ESC recommendations across prevention, diagnostic criteria, multimodality imaging, oral antibiotic therapy, surgical indications, and timing, and concluded that most could be endorsed.\"},{\"question\":\"What key clinical roles and treatment-related updates are highlighted in the endorsed statement?\",\"answer\":\"The statement reinforces the pivotal role of the Endocarditis Team, presents a refined antibiotic prophylactic regimen, and updates guidance for analysis of suspected blood culture-negative IE.\"}]","2023 European Society of Cardiology guidelines for the management of infective endocarditis - Statement of endorsement by the NVVC | PDF",1790751676,28]