[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-584471-105":59,"doc-detail-584471-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","2016-iacc-summary-of-advances-in-autism-spectrum-disorder-research-april-2017","2016 IACC Summary of Advances in Autism Spectrum Disorder Research - April 2017","","2016 IACC Summary of Advances in Autism Spectrum Disorder Research consolidates federal and community-informed progress across autism spectrum disorder (ASD) research. The report outlines advances organized by key public questions, covering early warning signs, mechanisms underlying observed differences, causal and prevention-relevant findings, evidence for treatments and interventions, and service access considerations. It also addresses future directions with emphasis on outcomes beyond childhood, supported by selected research articles and a mandated strategic monitoring framework led by the Interagency Autism Coordinating Committee.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/2016-iacc-summary-of-advances-in-autism-spectrum-disorder-research-april-2017/584471/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/2016-iacc-summary-of-advances-in-autism-spectrum-disorder-research-april-2017/584471.png","ImageObject",300,407,{"name":92,"@type":93},"WPS_1786070896","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-19","2026-10-15",true,{"@type":102,"interactionType":103,"userInteractionCount":81},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is the role of the Interagency Autism Coordinating Committee (IACC)?","Question",{"text":112,"@type":113},"The IACC coordinates U.S. Department of Health and Human Services activities related to ASD and provides advice to the Secretary of HHS on autism-related issues.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How is the 2016 summary organized?",{"text":117,"@type":113},"It is structured around major questions about concern, understanding, causes and prevention, effective treatments and interventions, service access, and future directions, with selected research articles under each topic.",{"name":119,"@type":110,"acceptedAnswer":120},"What responsibilities does the IACC have under the Children’s Health Act and related authorizations?",{"text":121,"@type":113},"The IACC must develop and annually update an ASD research strategic plan, develop and annually update a summary of advances in ASD research, and monitor federal activities related to ASD.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},584471,1792168216,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":81,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},549768072016,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","INTERAGENCY AUTISM COORDINATING COMMITTEE  \n2016  \nSUMMARY  \nOF ADVANCES  \nin Autism Spectrum Disorder Research  \nINTERAGENCY AUTISM COORDINATING COMMITTEE  \n2016  \nSUMMARY OF ADVANCES  \nin Autism Spectrum Disorder Research  \nCOVER DESIGN  \nNIH Medical Arts Branch  \nCOPYRIGHT INFORMATION  \nAll material appearing in this report is in the public domain and may be reproduced or copied. A suggested citation follows.  \nSUGGESTED CITATION  \nInteragency Autism Coordinating Committee (IACC). 2016 IACC Summary of Advances in Autism Spectrum Disorder Research. April 2017. Retrieved from the U.S. Department of Health and Human Services Interagency Autism Coordinating Committee website: [https://iacc.hhs.gov/publications/summary-of-advances/2016/](https://iacc.hhs.gov/publications/summary-of-advances/2016/).  \nii  \nABOUT THE IACC  \nThe Interagency Autism Coordinating Committee (IACC) is a Federal advisory committee charged with coordinating all activities concerning autism spectrum disorder (ASD) within the U.S. Department of Health and Human Services (HHS) and providing advice to the Secretary of HHS on issues related to autism. It was established by Congress under the Children’s Health Act of 2000, reconstituted under the Combating Autism Act (CAA) of 2006, and renewed under the Autism Collaboration, Accountability, Research, Education, and Support (CARES) Act of 2014.  \nMembership of the Committee includes a wide array of Federal agencies involved in ASD research and services, as well as public stakeholders, including self-advocates, family members of children and adults with ASD, advocates, service providers, and researchers, who represent a variety of perspectives from within the autism community. This IACC membership is composed to ensure that the Committee is equipped to address the wide range of issues and challenges faced by families and individuals affected by autism.  \nUnder the CAA and subsequent authorizations, the IACC is required to (1) develop and annually update a strategic plan for ASD research,(2) develop and annually update a summary of advances in ASD research, and (3) monitor Federal activities related to ASD.  \nThrough these and other activities, the IACC provides guidance to HHS and partners with the broader autism community to accelerate research and enhance services with the goal of profoundly improving the lives of people with ASD and their families.  \n***  \nFor more information about the IACC, see [http://www.iacc.hhs.gov](http://www.iacc.hhs.gov).  \niii  \nTABLE OF CONTENTS  \nINTRODUCTION  ........................................................................ vi  \nARTICLES SELECTED FOR THE 2016 SUMMARY OF ADVANCES  ............................ 1  \nQUESTION 1: WHEN SHOULD I BE CONCERNED?  ......................................... 2  \nReduced engagement with social stimuli in 6-month-old infants with later autism spectrum disorder: a longitudinal prospective study of infants at high familial risk  .......................... 2  \nSchool-age outcomes of infants at risk for autism spectrum disorder  ............................... 4  \nQUESTION 2: HOW CAN I UNDERSTAND WHAT IS HAPPENING?  ............................ 5  \nPeripheral mechanosensory neuron dysfunction underlies tactile and behavioral deficits in mouse model s of A SDs  ........................................................................ 5  \nGenome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism  ............7  \nGene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders  .. 8  \nQUESTION 3: WHAT CAUSED THIS TO HAPPEN AND CAN IT BE PREVENTED?  ............... 9  \nEffect of co-twin gender on neurodevelopmental symptoms: a twin register study  ................. 9  \nRisk of psychiatric and neurodevelopmental disorders among siblings of probands with  ..............  \nautism spectrum disorders  .................................................................... 10  \nAssociation betw","cbCairn1h5iWURRn","https://ap.wps.com/l/cbCairn1h5iWURRn","pdf",2156635,52,"English","# INTRODUCTION\n## ARTICLES SELECTED FOR THE 2016 SUMMARY OF ADVANCES\n## QUESTION 1: WHEN SHOULD I BE CONCERNED?\n## QUESTION 2: HOW CAN I UNDERSTAND WHAT IS HAPPENING?\n## QUESTION 3: WHAT CAUSED THIS TO HAPPEN AND CAN IT BE PREVENTED?\n## QUESTION 4: WHICH TREATMENTS AND INTERVENTIONS WILL HELP?\n## QUESTION 5: WHERE CAN I TURN FOR SERVICES?\n## QUESTION 6: WHAT DOES THE FUTURE HOLD, PARTICULARLY FOR ADULTS?","[{\"question\":\"What is the role of the Interagency Autism Coordinating Committee (IACC)?\",\"answer\":\"The IACC coordinates U.S. Department of Health and Human Services activities related to ASD and provides advice to the Secretary of HHS on autism-related issues.\"},{\"question\":\"How is the 2016 summary organized?\",\"answer\":\"It is structured around major questions about concern, understanding, causes and prevention, effective treatments and interventions, service access, and future directions, with selected research articles under each topic.\"},{\"question\":\"What responsibilities does the IACC have under the Children’s Health Act and related authorizations?\",\"answer\":\"The IACC must develop and annually update an ASD research strategic plan, develop and annually update a summary of advances in ASD research, and monitor federal activities related to ASD.\"}]","2016 IACC Summary of Advances in Autism Spectrum Disorder Research - April 2017 | PDF",1792051094,131]